Key result
Dual-tracer PET/CT supports perinephric myxoid pseudotumor of fat diagnosis and guides conservative management.
Case Report (n=1)
Dual-tracer PET/CT can aid in the non-invasive diagnosis of perinephric myxoid pseudotumor of fat, guiding conservative management.
May aid non-invasive diagnosis of rare perinephric lesions; leaves open validation in larger cohorts.
A 62-year-old man with biopsy-proven focal segmental glomerulosclerosis presented with nephrotic syndrome and enlarging bilateral perinephric masses. Contrast-enhanced CT showed large low-density lesions surrounding and compressing both kidneys, raising concern for retroperitoneal malignancy. Needle biopsy revealed bland spindle cells with low proliferative activity in myxoid stroma. Because he declined repeat biopsy, dual-tracer PET/CT was performed, showing diffuse mild-to-moderate 18F-FDG uptake (SUVmax, 6.5) and moderate 68Ga-FAPI uptake (SUVmax, 8.5), without focal markedly increased uptake. Integration of these imaging and pathologic findings supported the diagnosis of perinephric myxoid pseudotumor of fat and guided conservative management.
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Jiang et al. (2026) conducted a case report in Nephrotic syndrome and enlarging bilateral perinephric masses (n=1). Dual-tracer PET/CT (18F-FDG and 68Ga-FAPI) was evaluated on Diagnosis of perinephric myxoid pseudotumor of fat. Dual-tracer PET/CT showing diffuse mild-to-moderate 18F-FDG and moderate 68Ga-FAPI uptake supported the diagnosis of perinephric myxoid pseudotumor of fat and guided conservative management.
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