Key result
Lactate and shock index strongly predict 24-hour mortality in AHF.
Why the study?
The study compared the usefulness of shock index and lactate for predicting 24-hour and 28-day mortality in patients with acute heart failure presenting to the emergency department.
Do shock index and lactate predict 24-hour and 28-day mortality in acute heart failure patients in the emergency department?
Observational (n=112)
No
Do shock index and lactate predict 24-hour and 28-day mortality in acute heart failure patients in the emergency department?
Lactate level and shock index calculated in the ED triage are useful predictors of 24-hour and 28-day mortality in acute heart failure patients.
Lactate and SI may support early AHF risk assessment in the ED; leaves open incremental value over validated scores in larger cohorts.
OBJECTIVE: To compare the usefulness of shock index (SI) and lactate for prediction of 24-hour and 28-day mortality in acute heart failure (AHF) patients. STUDY DESIGN: A descriptive study. Place and Duration of the Study: Balikesir University Hospital, Balikesir, Turkey; from February 2019 to August 2020. METHODOLOGY: One hundred and twelve AHF patients presenting to ED were recruited into the study. Usefulness of lactate and SI in predicting mortality at 24-hour and 28-day, was evaluated. RESULTS: The area under the curve (AUC) was found to be 0.825 for lactate and 0.818 for SI in predicting 24-hour mortality. There was significant difference between the diagnostic performances of 2 markers in predicting 24-hour mortality. AUC was found to be 0.775 for lactate and 0.722 for SI in predicting 28-day mortality. No significant difference was found between the diagnostic performances of the two markers in predicting 28-day mortality. The 24-hour non-survivor rates were found to be 86.67% in patients with lactate levels >2.57; 76.47% in patients with SI >0.94, and 93.33% in patients with lactate levels >2.57 or SI >0.94. The 28-day non-survivor rates were found to be 64.71% in patients with lactate levels >2.57; 70.59% in patients with SI >0.82, and 82.35% in patients with lactate levels >2.57 or SI >0.82. CONCLUSION: Lactate level and SI of AHF patients calculated in ED triage may be used to predict mortality, and simultaneous use of both parameters may be more helpful.
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ÇETİNKAYA et al. (2021) conducted an observational in Acute heart failure (n=112). Shock index and lactate was evaluated on 24-hour and 28-day mortality. Lactate and shock index predicted 24-hour mortality in acute heart failure patients with AUCs of 0.825 and 0.818, respectively.
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