Key result
Laparoscopic sleeve gastrectomy is linked to ~9% lower epicardial fat thickness at four months.
Why the study?
Obesity contributes to vascular disease, and lipid deposition in cardiac tissues directly affects disease initiation and prognosis, motivating an assessment of the relationship between weight reduction and epicardial thickness after laparoscopic-sleeve gastrectomy.
Does laparoscopic-sleeve gastrectomy reduce epicardial fat thickness in morbidly obese patients?
Observational (n=42)
No
Does laparoscopic-sleeve gastrectomy reduce epicardial fat thickness in morbidly obese patients?
Absolute Event Rate: 111.26% vs 121.71%
p-value: p=<0.0001
Laparoscopic-sleeve gastrectomy in morbidly obese patients leads to a significant reduction in epicardial fat thickness, a surrogate marker for cardiovascular risk, at 4 months post-operation.
May support sleeve gastrectomy for epicardial fat reduction in obesity; leaves open effects on cardiovascular events.
Introduction: Obesity is increasingly reported to be a contributing factor to vascular diseases resulting in increased patient morbidity and mortality rates leading to increase healthcare expenses.More precisely, the lipid deposition in cardiac tissues is interesting, due to their direct contribution to the disease initiation, prognosis, and all subsequent patients' fate.We do focus on the determination of the link between changes in body mass index (BMI) and epicardial fat deposition concerning gastric operation.Objective: The objective of this work was to study the relationship between weight reduction and "epicardial thickness" after laparoscopic-sleeve gastrectomy.Methods: Critically-ill patients were recruited from private clinics and out-patients hospital clinics.Forty-two patients undergoing laparoscopic-sleeve gastrectomy due to morbid obesity were included in this research.Patients followed for four months after the operation.Results: The results of this work find there is significant weight reduction in these patients in parallel with a reduction of epicardial fat thickness. Conclusion:Patients who experience laparoscopic-sleeve gastrectomy showed a reduction in weight in a parallel reduction in epicardial fat thickness.
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Lolan et al. (2022) conducted an observational in Morbid obesity (n=42). Laparoscopic-sleeve gastrectomy vs. Baseline (pre-operation) was evaluated on Epicardial fat thickness at 4 months (p=<0.0001). Laparoscopic-sleeve gastrectomy significantly reduced epicardial fat thickness from 121.71 mm to 111.26 mm and BMI from 42.02 to 37.83 kg/m2 after four months (p<0.0001).
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