Key result
Radical surgery for renal cell carcinoma with intracardiac tumor thrombus carries ~8% in-hospital mortality.
Why the study?
Renal cell carcinoma with level IV tumor thrombus extension into the right atrium is a rare, life-threatening condition requiring combined urological and cardiac surgery, prompting analysis of early and late radical treatment outcomes.
Does radical surgery with DHCA improve survival in patients with RCC and intracardiac tumor thrombus extension?
Observational (n=37)
No
Does radical surgery with DHCA improve survival in patients with RCC and intracardiac tumor thrombus extension?
Radical surgical excision of RCC with intracardiac tumor thrombus using DHCA is feasible and yields a median survival of over 2 years.
No takes yet. Share an insight, caveat, or question.
May support radical surgery in select patients at experienced centers; leaves open randomized confirmation of survival benefit.
Žáček et al. (2023) conducted an observational in Renal cell carcinoma with intracardiac tumor thrombus extension (n=37). Radical surgery (nephrectomy and tumor thrombus extraction under deep hypothermic circulatory arrest) was evaluated on In-hospital mortality. Radical surgery for renal cell carcinoma with intracardiac tumor thrombus extension resulted in an in-hospital mortality of 7.9% and a 5-year cancer-related survival rate of 51%.
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