Key result
Six weeks of antibiotics successfully resolves infective endocarditis in a pregnant patient without surgery.
Why the study?
There is very limited guidance in current guidelines on treatment options for infective endocarditis during pregnancy.
Does antibiotic therapy alone cure infective endocarditis in a pregnant patient with mitral valve prolapse?
Case Report (n=1)
Does antibiotic therapy alone cure infective endocarditis in a pregnant patient with mitral valve prolapse?
Infective endocarditis during pregnancy can be successfully treated with medical therapy alone, and the authors suggest IE prophylaxis may be rational in MVP patients with mitral regurgitation despite current guidelines.
May guide individualized IE management in pregnancy; leaves open need for prospective data on optimal strategies.
During pregnancy, infective endocarditis (IE) is quite rare but has a high mortality rate in terms of the mother and the fetus. In this article, a 24-year-old patient with a history of mitral valve prolapse (MVP) who was hospitalized due to IE and treated successfully is presented. On echocardiography, severe mitral valve prolapse, severe mitral regurgitation, and vegetation on the posterior leaflet of mitral valve were observed. Streptococcus mitis was subsequently isolated from four sets of blood cultures. The patient was diagnosed with IE. After 6 weeks of antibiotic therapy, the patient was cured completely without surgical treatment. At 40-weeks of pregnancy, the patient gave birth via a normal vaginal delivery. There were no problems with the 3,800-gram baby born. In current guidelines, there is very limited advice on treatment options for patients who develop IE during pregnancy. Therefore, evaluation of patient-based treatment options would be appropriate. In addition, IE prophylaxis for MVP is not recommended in current guidelines. However, in MVP patients with mitral regurgitation, prior to procedures associated with a high risk of infective endocarditis, IE prophylaxis may be rational.
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Çalışkan et al. (2015) conducted a case report in Infective endocarditis during pregnancy (n=1). Antibiotic therapy was evaluated on Cure of infective endocarditis and pregnancy outcome. A 24-year-old pregnant patient with infective endocarditis and mitral valve prolapse was completely cured with 6 weeks of antibiotic therapy and delivered a healthy baby without surgical treatment.
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