Histopathological lauren classification of gastric carcinoma with biopsy specimen and a histological difference with dysplasia

Background: The aim of this study was to show whether endoscopic biopsy specimens are adequate quality to enable reliable classification of gastric cancer, about differentiation, the presence of signet ring cells, or histologic type, and a histological difference with Dysplasia.Method: In the present study, 154 patients with gastric carcinoma, with biopsy and surgical specimens were analyzed; and compared with the biopsy for suspected gastric carcinoma.In the gastric carcinoma biopsy specimens, (154 cases) the sensitivity and specificity were 86% and 82% respectively for intestinal type, and 87% and 90% respectively for the diffuse gastric carcinoma.The results of the pathology between endoscopic biopsy and surgical specimen analysis were 70%.Conclusion: In gastric carcinoma, the degree of misclassification is largely independent of whether the source of the material is a biopsy or surgical specimens, and this is important in the preoperative planning of the surgical strategy.