Key result
Elfin localizes to actin stress fibers, suggesting a role in myofibrillogenesis and mouse heart development.
Why the study?
Elfin expression during early heart development and its potential role in myofibrillogenesis and heart development were not fully characterized.
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No immediate clinical implications; leaves open functional role of Elfin in human cardiac development.
Kotaka et al. (2001) studied Heart development. Elfin expression was evaluated on Elfin localization and expression. Elfin localizes at the actin stress fibers of myoblasts and is expressed throughout the developing mouse heart, suggesting a role in myofibrillogenesis and heart development.
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