A de novo asymmetric synthesis of α‐ido‐pyranosides, as well as several deoxy and amino variants, has been achieved. The procedure involves a palladium(0)‐catalyzed glycosylation in combination with a Wharton rearrangement/epoxide‐opening reaction sequence to access sugars with ido, manno, and colito stereochemistry as well as several azido analogues.
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Cuccarese et al. (2013) studied this question.
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