Why the study?
Does diabetes mellitus influence plaque volume and vessel size at reference segments in patients undergoing percutaneous coronary intervention?
Population
344 patients with 449 de novo coronary lesions undergoing elective percutaneous coronary intervention under…
Comparison
Diabetes mellitus vs Non-diabetic patients
Design
Cohort
Key result
Diabetes mellitus was associated with a significantly larger percentage of plaque area (50.4% vs 46.5%) and smaller lumen area at reference segments compared to non-diabetic patients undergoing percutaneous coronary intervention.
Authors
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May prompt closer reference segment evaluation in diabetic PCI; leaves open effects on procedural and long-term outcomes.
Observational (n=344)
No
Does diabetes mellitus influence plaque volume and vessel size at reference segments in patients undergoing percutaneous coronary intervention?
Absolute Event Rate: 50.4% vs 46.5%
p-value: p=<0.001
Diabetic patients have smaller lumen areas and larger plaque burdens at reference segments, which may lead to undersized device selection if intravascular ultrasound guidance is not used during PCI.
Ito et al. (2004) conducted an observational in Coronary artery disease requiring percutaneous coronary intervention (n=344). Diabetes Mellitus vs. Non-diabetic patients was evaluated on Percentage plaque area (%PA) at reference segment (p=<0.001). Diabetes mellitus was associated with a significantly larger percentage of plaque area (50.4% vs 46.5%) and smaller lumen area at reference segments compared to non-diabetic patients undergoing percutaneous coronary intervention.