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Can low-risk patients with β-lactam allergy receive an oral β-lactam challenge safely? In adults with a history of nonsevere cutaneous reaction to a β-lactam more than 5 to 10 years ago, the penicillin allergy label can be removed 87% to 98% of the time. Direct oral challenge with a β-lactam
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Braschi et al. (2025) studied this question.
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