Key result
Lower serum hemoglobin linked to increased risk of depressive symptoms in CAPD patients.
Why the study?
The study was conducted to identify the prevalence of depressive symptoms and the factors associated with depressive symptoms in peritoneal dialysis patients.
Cross-Sectional (n=132)
No
Odds Ratio: 0.989 (95% CI 0.979–0.998)
p-value: p=0.023
Depression is highly prevalent in peritoneal dialysis patients, with lower serum hemoglobin identified as an independent risk factor.
May warrant anemia screening in peritoneal dialysis patients with depression; hypothesis-generating and requires prospective validation before practice change.
BACKGROUND: The aim of this study was to identify the prevalence of the depressive symptoms and the factors associated with the depressive symptoms in peritoneal dialysis patients. METHODS: A cross-sectional study was carried out to evaluate the prevalence and associated factors of depression in 132 continuous ambulatory peritoneal dialysis patients. Depression was evaluated using Zung Self-Rating Depression Scale. Sociodemographic and clinical characteristic were also investigated. Univariate analysis and multivariate logistic regression analysis were performed to select factors associated with depressive symptoms. RESULTS: Their median age was 57.5 years, and 58.3% were male. The rate of depressive symptoms in peritoneal dialysis patients was 78.0%. The rate of moderate/severe depressive symptoms was 64.4%. Multivariable logistic regression analysis showed that lower serum hemoglobin was significantly associated with increased risks of depression (OR = 0.989, 95CI%=0.979-0.998, p = 0.023). CONCLUSION: Depression was highly prevalent in the peritoneal dialysis patients. Serum hemoglobin was independent risk factor for depressive symptoms in peritoneal dialysis patients.
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Chen et al. (2023) conducted a cross-sectional in End-stage renal disease receiving continuous ambulatory peritoneal dialysis (n=132). Serum hemoglobin was evaluated on Depressive symptoms (OR 0.989, 95% CI 0.979-0.998, p=0.023). Lower serum hemoglobin was independently associated with an increased risk of depressive symptoms in continuous ambulatory peritoneal dialysis patients (OR 0.989).
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