Key result
CTA-fluoroscopy image fusion enables successful TEVAR using zero intraoperative iodinated contrast.
Why the study?
Catheter-based 2-dimensional angiography is routinely performed before, during, and after stent-graft placement in TEVAR, while recent advances allow overlaying live fluoroscopy over preacquired CTA. This report describes the first case of TEVAR guided by CTA superimposed on live fluoroscopy without using iodinated contrast agent during the procedure.
Case Report (n=1)
No
This case report demonstrates the feasibility of performing thoracic endovascular aortic repair (TEVAR) without iodinated contrast by fusing preacquired CTA with intraoperative cone-beam CT and live fluoroscopy.
Suggests zero-contrast TEVAR feasibility via fusion; leaves open prospective validation before clinical adoption.
I n recent years, thoracic endovascular aortic repair (TEVAR) has been established as a reliable alternative to conventional surgical repair. 1 The success of endovascular repair is critically dependent on adequate stent-graft deployment.Catheter-based 2-dimensional angiography is routinely performed before, during, and after stent-graft placement to ensure accurate positioning and confirm the absence of complications such as perigraft endoleaks.Computed tomography angiography (CTA) is also used to plan stent-graft deployment before intervention.Recent advances in imaging technology allow reusing the diagnostic volumetric data sets during intervention by overlying live fluoroscopy over the preacquired CTA. 2 This article describes the first case of TEVAR under guidance of CTA superimposed on live fluoroscopy without the use of iodinated contrast agent before, during, and after deployment.An 82-year-old man was admitted to the hospital with an asymptomatic thoracic aneurysm of 65-mm diameter on the descending aorta extending from 85 mm below the left subclavian artery to 120 mm above the celiac trunk (Figure 1).Ten years earlier, the patient had undergone surgical repair of an abdominal aortic aneurysm.No other comorbidities existed.Given the age of the patient, he was scheduled for endovascular treatment with a thoracic aortic stent graft.Endovascular navigation and stent-graft deployment were achieved using superimposition of preacquired volumetric CTA data on live 2-dimensional fluoroscopy (MR/CT Roadmap, Philips Healthcare, Best, the Netherlands).The CTA was acquired Ϸ1 hour before the patient was transferred to the interventional suite for placement of the thoracic stent graft.For registration of the live fluoroscopy with the CTA volume, a low-dose cone-beam CT acquisition (XperCT, Philips Healthcare) without injection of iodinated contrast was acquired after induction of general anesthesia and before draping the patient.During patient preparation, the preacquired CTA volume was fused with the intraoperative conebeam CT.This has the effect of bringing the CTA volume into the same coordinate space as the live fluoroscopy, thus allowing fluoroscopic navigation over the diagnostic CTA. 2
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Kobeiter et al. (2011) conducted a case report in Asymptomatic descending thoracic aortic aneurysm (n=1). Zero-contrast thoracic endovascular aortic repair (TEVAR) using image fusion of preacquired CTA and intraoperative cone-beam CT on live fluoroscopy was evaluated on Successful endovascular navigation and thoracic stent-graft deployment without iodinated contrast. Thoracic endovascular aortic repair using CTA-fluoroscopy image fusion achieved stent-graft deployment in an 82-year-old man with a 65-mm aneurysm using 0 mL of intraoperative iodinated contrast.
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