Key result
Flow-reversal and aspiration thrombectomy successfully treats immediate carotid stent thrombosis due to clopidogrel resistance.
Why the study?
Preoperative antiplatelet resistance testing remains debated, and management strategies for immediate carotid stent thrombosis after transcarotid artery revascularization require description.
Case Report (n=1)
Flow-reversal and aspiration thrombectomy can successfully rescue immediate post-TCAR carotid stent thrombosis caused by clopidogrel resistance.
May inform rescue strategies for acute carotid stent thrombosis with clopidogrel resistance; hypothesis-generating case report requiring prospective validation.
An 84-year-old patient developed immediate thrombosis of his carotid stent in recovery after transcarotid artery revascularization. In the present report, the technical details about intraoperative management for neurovascular rescue using the transcarotid artery revascularization flow-reversal system are described. The patient was determined to have clopidogrel resistance. Intraoperative medical management is also discussed. The current alternative intravenous and oral antiplatelet therapies such as glycoprotein IIb/IIIa and P2Y12 inhibitors are explored. The debate regarding preoperative antiplatelet resistance testing remains ambiguous, and increasing studies have demonstrated the safety and efficacy of alternatives to clopidogrel. Despite an unpredictable and devastating complication, the patient's outcome was successful using contemporary strategies.
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Joyce Lu (2023) conducted a case report in Carotid stent thrombosis due to clopidogrel resistance (n=1). Flow-reversal system and aspiration thrombectomy was evaluated on Patient outcome. Neurovascular rescue using a flow-reversal system and aspiration thrombectomy successfully treated immediate carotid stent thrombosis due to clopidogrel resistance.
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