Two cases of mucinous adenocarcinoma of the renal pelvis are added to those so far reported in the literature. The frequency of long-standing, chronic infection, and large renal calculi associated with this tumor is emphasized, and these conditions are invoked as possible etiologic factors. The hazard of development of this tumor is a factor to be included in the consideration of a therapeutic plan for the patient with a large renal calculus. The occult gross structure of some of these tumors may lead both surgeon and pathologist to overlook their presence. Routine frozen sections on kidneys removed because of large calculi would obviate this.
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Aufderheide et al. (1974) studied this question.
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