Key result
High-degree AV block in inferior AMI is linked to ~6-fold higher in-hospital mortality.
Why the study?
The long-term prognostic significance of atrioventricular block in patients with inferior acute myocardial infarction was unclear.
Does the development of 2nd or 3rd degree AV block affect in-hospital and long-term mortality in patients with inferior acute myocardial infarction?
Population
477 consecutive patients admitted for inferior AMI
Comparison
Patients with 2nd or 3rd degree AV block (n=88) vs without AV block (n=359)
Design
Cohort study
Follow-up
3 years post-hospital
Authors
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AV block in inferior AMI signals high in-hospital mortality risk; leaves open whether targeted interventions improve survival beyond discharge.
Cohort (n=477)
Does the development of 2nd or 3rd degree AV block affect in-hospital and long-term mortality in patients with inferior acute myocardial infarction?
Absolute Event Rate: 24% vs 4%
p-value: p=<0.001
While the development of 2nd or 3rd degree AV block in inferior AMI is associated with higher in-hospital mortality, it does not adversely affect the long-term prognosis of patients who survive to hospital discharge.
Dubois et al. (1989) conducted a cohort in inferior acute myocardial infarction (n=477). 2nd or 3rd degree atrioventricular block vs. No atrioventricular block was evaluated on In-hospital mortality (p=<0.001). Development of 2nd or 3rd degree AV block in inferior AMI was associated with higher in-hospital mortality (24% vs 4%, P<0.001), but similar 3-year post-hospital mortality among survivors.
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