Key result
ICU ultrasound yields specific femoral thickness and area cut-offs for muscle mass assessment versus CT.
Why the study?
Ultrasound is an important tool to assess muscle mass at ICU admission, but established cut-off values are currently lacking.
What are the cut-off values for ultrasound-based muscle mass assessment compared to CT-derived skeletal muscle index in ICU patients?
Observational
What are the cut-off values for ultrasound-based muscle mass assessment compared to CT-derived skeletal muscle index in ICU patients?
This study proposes sex-specific cut-off values for ultrasound-based muscle mass assessment at ICU admission, using CT-derived skeletal muscle index as a reference.
May offer bedside CT alternative for ICU muscle assessment; leaves open prospective outcome validation before practice adoption.
Background and aims Muscle mass is an important component of nutritional status. At intensive care unit (ICU) admission, ultrasound is an important tool to assess the muscle mass, but there are currently no established cut-off values. Therefore, we retrospectively analyzed cut-off values for an ultrasound-based muscle mass assessment at ICU admission. Methods We retrospectively analyzed data collected in an observational study. These data included a muscle mass assessment of lower limb thickness and cross-sectional area (CSA), upper limb thickness and CSA, and diaphragm thickness at ICU admission. Skeletal muscle mass was calculated from computed tomography (CT) imaging of the third lumbar vertebra for comparison. Cut-off values were estimated from the relationship between the ultrasound-based muscle mass assessment and CT-derived skeletal muscle index at 7.0 kg/m 2 in males and 5.4 kg/m 2 in females. Results Lower limb, upper limb, and diaphragm assessments included 89, 52, and 79 patients, respectively. The age was 70 ± 13 years and body mass index was 22.2 ± 4.4 kg/m 2 . Cut-off values were 22.5 mm (male) and 19.0 mm (female) for femoral thickness and 5.0 cm 2 (male) and 4.5 cm 2 (female) for rectus femoris CSA. Cut-off values were 26.9mm (male) and 20.6 mm (female) for upper limb thickness and 6.5 cm 2 (male) and 4.0 cm 2 (female) for biceps brachii CSA. Cut-off values were 1.8 mm (male) and 1.5 mm (female) for diaphragm. Conclusion We proposed cut-off values for ultrasound-based muscle mass assessment at ICU admission. Further studies are needed to validate these cut-off values.
No takes yet. Share an insight, caveat, or question.
Nakanishi et al. (2024) conducted an observational in Intensive care unit admission. Ultrasound-based muscle mass assessment vs. CT-derived skeletal muscle index was evaluated on Cut-off values for ultrasound-based muscle mass assessment. Ultrasound-based muscle mass assessment at ICU admission yielded specific cut-off values for femoral thickness (22.5 mm male, 19.0 mm female) and rectus femoris CSA (5.0 cm2 male, 4.5 cm2 female).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: