Key result
≥5 stressful life events are linked to elevated cardiometabolic risk in gay and bisexual adults.
Why the study?
It was unclear whether sexual minority young adults are more vulnerable to developing cardiometabolic risk following exposure to stressful life events than heterosexual young adults.
Does exposure to stressful life events increase cardiometabolic risk more in sexual minority young adults compared to heterosexual young adults?
Cohort (n=6,973)
Yes
Does exposure to stressful life events increase cardiometabolic risk more in sexual minority young adults compared to heterosexual young adults?
Effect estimate: β = 0.87
p-value: p=0.01
Stressful life events during childhood and adolescence place lesbian, gay, and bisexual young adults at a heightened risk for elevated cardiometabolic risk compared to their heterosexual peers.
May warrant stress-informed cardiometabolic screening in sexual minority youth; leaves open differential impact versus heterosexual peers and causal confirmation.
OBJECTIVE: The goal of the present study was to examine whether sexual minority young adults are more vulnerable to developing cardiometabolic risk following exposure to stressful life events than heterosexual young adults. METHOD: Data came from the National Longitudinal Study for Adolescent Health (Shin, Edwards, & Heeren, 2009; Brummett et al., 2013), a prospective nationally representative study of U.S. adolescents followed into young adulthood. A total of 306 lesbian, gay, and bisexual (LGB) respondents and 6,667 heterosexual respondents met inclusion criteria for this analysis. Measures of cumulative stressful life events were drawn from all 4 waves of data collection; sexual orientation and cardiometabolic biomarkers were assessed at Wave 4 (2008-2009). RESULTS: Gay/bisexual men exposed to 1-2 (β = 0.71, p = .01) and 5+ (β = 0.87, p = .01) stressful life events had a statistically significant elevation in cardiometabolic risk, controlling for demographics, health behaviors, and socioeconomic status. Moreover, in models adjusted for all covariates, lesbian/bisexual (β = 0.52, p = .046) women with 5+ stressful life events had a statistically significant elevation in cardiometabolic risk. There was no relationship between stressful life events and cardiometabolic risk among heterosexual men or women. CONCLUSION: Stressful life events during childhood, adolescence, and young adulthood place LGB young adults at heightened risk for elevated cardiometabolic risk as early as young adulthood. The mechanisms underlying this relationship require future study.
No takes yet. Share an insight, caveat, or question.
Hatzenbuehler et al. (2014) conducted a cohort in Cardiometabolic risk (n=6,973). Stressful life events vs. Heterosexual young adults was evaluated on Cardiometabolic risk (β = 0.87, p=0.01). Exposure to 5 or more stressful life events was associated with significantly elevated cardiometabolic risk in gay/bisexual men (β=0.87, p=0.01) and lesbian/bisexual women (β=0.52, p=0.046).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: