Key result
Age and neutrophil-lymphocyte ratio predict prolonged postoperative ileus, affecting ~38% of patients.
Why the study?
To explore the relationship between inflammatory markers and prolonged postoperative ileus, and to establish a nomogram for predicting it.
Can a nomogram based on age and inflammatory markers predict prolonged postoperative ileus in patients with colorectal cancer?
Observational (n=229)
Can a nomogram based on age and inflammatory markers predict prolonged postoperative ileus in patients with colorectal cancer?
A nomogram incorporating age and neutrophil-lymphocyte ratio dynamics can predict prolonged postoperative ileus in colorectal cancer patients.
May aid ileus risk stratification via nomogram in colorectal cancer surgery; leaves open prospective validation before clinical adoption.
Aim: To explore the relationship between inflammatory markers and prolonged postoperative ileus (PPOI), and to establish a nomogram for predicting PPOI. Patients & methods: The data of 229 patients were analyzed retrospectively. Univariate and multivariate logistic regression analysis were used to analyze the risk factors affecting the occurrence of PPOI. The predictive model of PPOI was established and verified internally. Results: Postoperative PPOI occurred in 87 (38.0%) of all 229 patients. Our study showed that age, preoperative neutrophil–lymphocyte ratio and changes in neutrophil–lymphocyte ratio were independent risk factors for PPOI. Conclusion: The nomograms established based on these independent risk factors have good predictive efficacy and may be able to guide clinicians to individualize the diagnosis and treatment.
No takes yet. Share an insight, caveat, or question.
Fan et al. (2023) conducted an observational in Colorectal Cancer (n=229). Age and inflammatory markers (neutrophil-lymphocyte ratio) was evaluated on Prolonged postoperative ileus (PPOI). Age, preoperative neutrophil-lymphocyte ratio, and changes in neutrophil-lymphocyte ratio were independent risk factors for prolonged postoperative ileus, which occurred in 38.0% of patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: