Key result
Flow cytometric VASP phosphorylation identifies impaired clopidogrel responsiveness in subacute stent thrombosis.
Why the study?
Is impaired platelet responsiveness to clopidogrel associated with subacute stent thrombosis?
Is impaired platelet responsiveness to clopidogrel associated with subacute stent thrombosis?
Impaired platelet responsiveness to clopidogrel can be identified using VASP phosphorylation in patients with subacute stent thrombosis.
VASP assay detects clopidogrel hyporesponsiveness in subacute stent thrombosis; hypothesis-generating and should not yet change practice.
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Faure et al. (2007) studied this question. Flow cytometric VASP phosphorylation identifies impaired platelet responsiveness to clopidogrel in patients with subacute stent thrombosis.
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