Why the study?
Does VASP phosphorylation measurement predict the risk of stent thrombosis in high-risk patients on dual antiplatelet therapy?
Population
99 patients with an elevated high risk to develop stent thrombosis, receiving dual antiplatelet therapy
Design
Cohort
Follow-up
6 months
Authors
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VASP-PRI may aid stent thrombosis risk stratification on DAPT; hypothesis-generating and requires prospective validation before guiding therapy.
Does VASP phosphorylation measurement predict the risk of stent thrombosis in high-risk patients on dual antiplatelet therapy?
VASP phosphorylation measurement is a strong independent predictor of stent thrombosis in high-risk patients on clopidogrel and aspirin, with a VASP-PRI >48% indicating significantly increased risk.
Stellbrink et al. (2007) studied this question.
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