Key result
Personal medical history remains the sole risk factor linked to high total cholesterol.
Why the study?
The most prevalent cardiovascular risk factor among the Malaysian population remained unknown amidst rapid urbanization and lifestyle changes.
Case-Control (n=180)
No
p-value: p=<0.05
In a multiethnic Malaysian cohort, cardiovascular risk factors were largely independent of total cholesterol status, though the significance of specific risk and protective factors varied by ethnicity.
Personal medical history may guide cholesterol assessment in multiethnic Malaysians; leaves open independent roles of other risk factors by ethnicity.
Malaysia is currently experiencing an epidemiologic and demographic transition. Rapid urbanization and vast changes in lifestyles among the population has led to widespread cardiovascular disease (CVD) outcomes. Also, until now, the most prevalent cardiovascular risk factor has remained unknown among the Malaysian population. This study aimed to identify the most significant cardiovascular risk factor among multiethnic adults in Dengkil, Selangor. A case-control retrospective study comparing past exposure (retrospective) between the case (total cholesterol (TC) ≥ 5.18 mmol/L) and control groups (TC < 5.18 mmol/L) on CVD risk via guided questionnaire comprised of International Physical Activity Questionnaire (IPAQ), Food Frequency Questionnaire (FFQ), Depression, Anxiety and Stress Scales (DASS)-21 and SF-12 was carried out among 180 respondents aged 20 to 56 years in Dengkil, Selangor. In the present study, purposive and consecutive sampling were both applied to recruit respondents and also considering ethnic as a factor; thus, quota sampling was also conducted. The data were analyzed using Mann-Whitney, Kruskal-Wallis, Chi-Square, Independent Samples t-test and multiple logistic regression tests. The findings indicated there were no significant differences (p > 0.05) regarding all the risk factors between the case and control groups except for personal medical history (p < 0.05). Chinese possessed the highest number of significant risk and protective factors. Lastly, the quality of life of Malay controls was higher than that of cases in terms of Physical Component Summary (PCS). Generally, all the risk factors were independent in terms of total cholesterol status, except for personal medical history. The significance of risk factors and protective factors varies according to ethnicity.
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Lee et al. (2020) conducted a case-control in Cardiovascular disease risk (n=180). Lifestyle and psychological risk factors was evaluated on Differences in risk factors between cases (TC ≥ 5.18 mmol/L) and controls (TC < 5.18 mmol/L) (p=<0.05). Personal medical history was the only risk factor significantly associated with total cholesterol status (p < 0.05) among multiethnic adults in Selangor.
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