Key result
Clinical impression of frailty linked to ~114% higher all-cause mortality in vascular surgical patients.
Why the study?
Recognising frailty during pre-operative assessment is important because frail patients have higher mortality and worse functional recovery after surgery.
Does an initial clinical impression of frailty predict all-cause mortality in vascular surgical patients?
Cohort (n=392)
Does an initial clinical impression of frailty predict all-cause mortality in vascular surgical patients?
Hazard Ratio: 2.14 (95% CI 1.51–3.05)
An initial clinical impression of frailty is a strong predictor of medium-term all-cause mortality in vascular surgical patients, serving as a useful screening tool.
May aid preoperative risk stratification in vascular surgery; leaves open whether frailty assessment should guide interventions.
Recognising frailty during pre-operative assessment is important. Frail patients experience higher mortality rates and are less likely to return to baseline functional status following the physiological insult of surgery. We evaluated the association between an initial clinical impression of frailty and all-cause mortality in 392 patients attending our vascular pre-operative assessment clinic. Prevalence of frailty assessed by the initial clinical impression was 30.6% (95% CI 26.0-35.2%). There were 133 deaths in 392 patients over a median follow-up period of 4 years. Using Cox regression, adjusted for age, sex, revised cardiac risk index and surgery (yes/no), the hazard ratio for mortality for frail vs. not-frail was 2.14 (95% CI 1.51-3.05). The time to 20% mortality was 16 months in the frail group and 33 months in the not-frail group. The initial clinical impression is a useful screening tool to identify frail patients in pre-operative assessment.
No takes yet. Share an insight, caveat, or question.
O'Neill et al. (2016) conducted a cohort in Vascular surgical patients (n=392). Initial clinical impression of frailty vs. Not-frail was evaluated on All-cause mortality (HR 2.14, 95% CI 1.51-3.05). An initial clinical impression of frailty in vascular surgical patients predicted higher all-cause mortality compared to not-frail patients (HR 2.14; 95% CI 1.51-3.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: