Methyl-3-indole carboxylate (3-indole carboxylic acid methyl ester [ICA. Me]) was identified in liquid cultures of Septoria tritici. For physiological studies, ICA. Me was synthesized from commercial 3-indole carboxylic acid (ICA) by methylation with diazomethane. Inhibition of growth of the melanin-producing isolate ISR398 by ICA.Me on thin-layer chromatography (TLC) plates was recorded at a concentration of 0.02 mg/ml. Inhibition by 3-indole acetic acid (IAA) was recorded at a concentration of 25-fold, whereas no inhibition was recorded for ICA at a concentration range of 0.02-0.5 mg/ml (...)
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Noga Zelikovitch (1992) studied this question.