Key result
Acute normovolemic hemodilution improves ECMO outflow in a patient with severe polycythemia.
Why the study?
Does acute normovolemic hemodilution improve extracorporeal membrane oxygenation outflow in patients with severe polycythemia and hyperviscosity?
Case Report (n=1)
Does acute normovolemic hemodilution improve extracorporeal membrane oxygenation outflow in patients with severe polycythemia and hyperviscosity?
Acute normovolemic hemodilution may effectively improve ECMO outflow in patients experiencing inadequate flow due to severe polycythemia and hyperviscosity.
May support ANH trial in select polycythemic ECMO cases; hypothesis-generating and requires prospective validation.
We report the case of a 47 year old male who developed acute respiratory distress syndrome after bariatric surgery, requiring a venovenous extracorporeal membrane oxygenation. An inadequate extracorporeal membrane oxygenation output flow was observed, possibly because of severe polycythemia and hyperviscosity. Management with acute normovolemic hemodilution corrected both the biologic and hemodynamic parameters. To our knowledge, this is the first reported case of acute normovolemic hemodilution to improve extracorporeal membrane oxygenation outflow. Clinicians should be aware that polycythemia and hyperviscosity may impair extracorporeal membrane oxygenation support and that acute normovolemic hemodilution may be a safe and efficient procedure to address such matter. The optimal hemoglobin level on extracorporeal membrane oxygenation deserves further investigation.
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Ursulet et al. (2019) conducted a case report in Acute respiratory distress syndrome (n=1). Acute normovolemic hemodilution was evaluated on Extracorporeal membrane oxygenation output flow. Acute normovolemic hemodilution successfully corrected biologic and hemodynamic parameters to improve extracorporeal membrane oxygenation outflow in a patient with severe polycythemia.
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