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The exponential increase in Big Data generation combined with limited capitalization on the wealth of information embedded within Big Data have prompted us to revisit our scientific discovery paradigms. A successful transition into this digital era of medicine holds great promise for advancing fundamental knowledge in biology, innovating human health and driving personalized medicine, however, this will require a drastic shift of research culture in how we conceptualize science and use data. An e-transformation will require global adoption and synergism among computational science, biomedical research and clinical domains.
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Scruggs et al. (2015) studied this question.
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