Key result
RAS blockers and lifestyle interventions for diabetic hypertension reduce cardiovascular disease risk.
Why the study?
Diabetes mellitus and hypertension are interrelated conditions that increase cardiovascular disease risk, requiring updated management strategies to improve outcomes.
Management of hypertension in patients with diabetes using a multidisciplinary approach and appropriate pharmacotherapy is crucial for reducing cardiovascular disease risk.
Supports RAS blockers plus lifestyle interventions in diabetic hypertension; leaves open need for updated RCTs on optimal regimens.
Diabetes mellitus and hypertension are interrelated conditions that predispose patients to cardiovascular disease. The 2015 American Diabetes Association guidelines recommend a blood pressure goal of <140/90 but indicates that a lower goal can be set for some individuals if this can be achieved without undue burden. Renin angiotensin system blockers remain the main stay of treatment in hypertensive diabetics together with lifestyle interventions. Guidelines indicate that combination therapy may be initiated in patients who have a blood pressure 20/10 over the target BP. As discussed in this review, there are several diabetic medications that have antihypertensive effects. Management of hypertension in diabetes mellitus is an important factor in reducing cardiovascular disease in conjunction with other cardiovascular disease prevention strategies such as use of stains and aspirin. Patients will benefit from multidisciplinary team expertise including a primary care provider, endocrinologist, hypertension specialist, diabetic educator and dietician.
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Khangura et al. (2015) conducted a review in Hypertension and diabetes mellitus. Antihypertensive therapy was evaluated. Management of hypertension in diabetes using renin angiotensin system blockers and lifestyle interventions is an important strategy for reducing cardiovascular disease.
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