Triple Therapy in Type 2 Diabetes: Insulin Glargine or Rosiglitazone Added to Combination Therapy of Sulfonylurea Plus Metformin in Insulin-Naive Patients

Rosenstock et al. (1) reported on the safety and efficacy of add-on insulin glargine versus rosiglitazone for patients with type 2 diabetes not adequately controlled on dual oral therapy with sulfonylurea plus metformin. The main finding of the study was similar glycemic control in both groups. About 50% of participants in both groups achieved an HbA1c of <7%. However, the authors comment on two …