Key result
Viral infections account for ~48% of diarrhea cases in young children, predominantly rotavirus and calicivirus.
Why the study?
Diarrhea is a leading cause of pediatric death, but few studies have evaluated viral diarrhea and the distribution of viruses across Shenyang in children under 5 years of age.
Cross-Sectional (n=897)
No
Viral infections, particularly rotavirus, are a major cause of diarrhea in children under 5 in Shenyang, highlighting the need for targeted public health measures.
Supports viral surveillance in pediatric diarrhea; hypothesis-generating for targeted interventions against predominant pathogens.
Diarrhea is one of the leading causes of death among children, especially in the age under 5, but few studies are available on viral diarrhea in Shenyang. To understand the infection status and the relevant epidemiological characteristics of viral diarrhea and to fill gaps of the distribution of viruses across Shenyang in children under the age of 5 with diarrhea, from 2018 to 2020, stool specimens of children with diarrhea aged 0-59 months and surveillance data were collected in Sentinel Hospital of Shenyang. Specimens were then tested to determine the type of viruses, the seasonal and spatial patterns for major viruses were determined. Viruses were identified in 47.9% of the 897 samples from children with diarrhea. The main viruses of stool samples were rotavirus (16.9%, predominant type G9P[8]), calicivirus (14.7%), adenovirus (11.8%), and astrovirus (4.5%). Viral infections were mainly detected in the age of 0-12 months. In the area of Shenyang, Huanggu had the most cases (198, 22.1%), followed by Dadong (137, 15.3%) and Hunnan (135, 15.1%). The positive rate of viruses varied among patients of different ages, seasons, and regions. Public health entities and the government should develop corresponding measures for different age groups, seasons, and regions.
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Dong et al. (2021) conducted a cross-sectional in Diarrhea (n=897). Viral infection was evaluated on Presence of viral infection in stool samples. Viral infections were identified in 47.9% of children under 5 with diarrhea, predominantly rotavirus (16.9%) and calicivirus (14.7%).
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