Key result
Critically ill cancer patients face ~18% ICU mortality, driven by septic shock and multiple organ failure.
Why the study?
ICU admission of critically ill cancer patients remains controversial due to prognosis, with survival benefits depending on factors that vary over time.
Cross-Sectional (n=232)
No
Critically ill cancer patients admitted to the ICU have a relatively high survival rate at discharge (>80%), supporting the benefit of intensive care in this population.
Supports ICU admission for selected cancer patients; leaves open need for prospective studies on septic shock prevention.
Introduction: Admission to intensive care unit (ICU) of critically ill cancer patients is controversial because of their prognosis, although there is evidence showing short-and medium-term survival benefits.However, this depends on a number of factors that may vary over time, which must be constantly studied. Methods:Retrospective cross-sectional study that evaluated mortality and related factors in critically ill cancer patients admitted to intensive care in a tertiary referral center in Colombia for one year.A descriptive analysis was performed.Results: Of 410 critically ill cancer patients, 232 met the inclusion criteria.55% of the population was male and were mainly between 50 -79 years old (mean 62.91 ± 14.3).The most frequently observed cancers were of gastrointestinal origin (26.7%), followed by hematologic cause (25.4%).At ICU discharge, 191 (82.3%) patients were alive.Among the most common causes of death, septic shock was found (26.8%), followed by multiple organ failure (14.6%).Of those who died, 70.7% had a history of surgery due to cancer, followed by hypertension and diabetes mellitus with 36.5% and 24.3%, respectively, and the most frequent indication for ICU admission was invasive mechanical ventilation in 63.4% of the cases, followed by the use of vasopressors in 60.9%.Conclusions: This study found that the mortality of critically ill cancer patients admitted to the ICU was less than 20%.The main cause of admission was postoperative monitoring, followed by vasopressor requirement and sepsis.The main causes of death were septic shock and multiple organ failure.
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Baez et al. (2023) conducted a cross-sectional in Critically ill cancer (n=232). Intensive care unit admission was evaluated on Mortality at ICU discharge. Mortality among critically ill cancer patients admitted to the intensive care unit was 17.7%, with the main causes of death being septic shock and multiple organ failure.
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