Key result
Pre-vaccine rotavirus appears in ~25% of tested Argentine samples, primarily in children under two.
Why the study?
Rotavirus is a major cause of acute diarrhea and child mortality in Argentina, and pre-vaccine epidemiology data were needed to assess baseline frequency, seasonality, age distribution, and genotypes.
Population
Children under 5 years with acute diarrhea in Argentina, 2012-2014
Design
Observational surveillance study using Viral Diarrhea Notification module data
Follow-up
2012-2014 period
Authors
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Sets pre-vaccine rotavirus baseline in Argentina; leaves open post-vaccine impact assessment in children under 2.
Observational
Yes
This study establishes the pre-vaccine baseline epidemiology and genotype distribution of rotavirus in Argentina, showing a 25% detection rate primarily in children under 2 years old.
Degiuseppe et al. (2016) conducted an observational in Rotavirus infection / Acute diarrhea. Pre-vaccine period (2012-2014) was evaluated on Rotavirus detection rate. In the pre-vaccine period of 2012-2014 in Argentina, rotavirus was detected in approximately 25% of tested samples, with higher rates observed in children under 2 years old.
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