Signal‐Amplifying Conjugated Polymer–DNA Hybrid Chips

Expand on that: Signal-amplifying DNA chips have been fabricated by a light-directed on-chip DNA synthesis on a thin film of a photostable conjugated polyoxadiazole derivative. The fluorescence signal from a hexachlorofluorescein-labeled target DNA was increased by a large amount through efficient Förster energy transfer from the conjugated polymer to the dye after DNA–DNA hybridization when compared with the signal from a control slide.