Key result
Compound obesity linked to ~370% greater hypertension risk, alongside increased dyslipidemia and diabetes.
Why the study?
The association between different types of obesity and chronic diseases in Dehui, Jilin province, China, was unclear.
Are different types of obesity associated with common vascular and metabolic diseases in adults aged 40 years or older?
Cross-Sectional (n=4,052)
Are different types of obesity associated with common vascular and metabolic diseases in adults aged 40 years or older?
Compound obesity and central obesity alone are strongly associated with metabolic diseases, while compound obesity is additionally associated with an increased risk of coronary heart disease.
Answers are grounded in this paper and cite their sources.
Supports obesity subtyping for cardiometabolic risk assessment in adults ≥40; leaves open causality and intervention effects.
Background: The association between different types of obesity and some chronic diseases in Dehui, Jilin province, China, is still unclear. The aim of our study was to clarify the association between different types of obesity and chronic diseases. Methods: Residents aged 40 years or older were randomly selected using a multistage stratified cluster sampling method. Data were collected by means of face-to-face interview, physical examination and laboratory examination. Descriptive data analyses were performed, and multiple logistic regression analyses were used to explore the adjusted association between different types of obesity and common vascular and metabolic diseases. Results: The prevalence of general obesity alone, central obesity alone and compound obesity were 0.15%, 54.29% and 14.36%, respectively. The prevalence of coronary heart disease, stroke, hypertension, dyslipidemia and diabetes mellitus was highest in the compound obesity group, and lowest in the non-obesity group. Hypertension, dyslipidemia, and diabetes mellitus were associated with compound obesity and central obesity alone (compound obesity [OR=4.703, 95% CI: 3.714-5.956 for hypertension; OR=4.244, 95% CI: 3.357-5.365 for dyslipidemia; OR=4.575, 95% CI: 3.194-6.552 for diabetes mellitus]; central obesity alone [OR=2.210, 95% CI: 1.901-2.570 for hypertension; OR=2.598, 95% CI: 2.241-3.012 for dyslipidemia; OR=2.519, 95% CI: 1.834-3.459 for diabetes mellitus]). Coronary heart disease was associated with compound obesity (OR=1.761, 95% CI: 1.141-2.719) but not central obesity alone (OR=1.409, 95% CI: 0.986-2.013). Stroke was associated with neither compound obesity (OR=1.222, 95% CI: 0.815-1.833) nor associated with central obesity alone (OR=1.080, 95% CI: 0.786-1.485). Conclusions: Central obesity alone and compound obesity are associated with the risk of hypertension, hyperlipidemia and diabetes mellitus. Compound obesity but not central obesity alone is associated with the risk of coronary heart disease, but further research is needed to confirm it. There are no significant relationship between stroke and central obesity alone or compound obesity.
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Zhang et al. (2020) conducted a cross-sectional in Obesity and chronic vascular and metabolic diseases (n=4,052). Compound obesity vs. Non-obesity was evaluated on Hypertension (OR 4.703, 95% CI 3.714-5.956, p=<0.001). Compound obesity was strongly associated with an increased risk of hypertension (OR 4.703), dyslipidemia (OR 4.244), and diabetes mellitus (OR 4.575) compared to non-obese individuals.
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