Key result
Metabolically unhealthy obesity is linked to ~144% higher CVD prevalence versus metabolically healthy normal weight.
Why the study?
There is a paucity of research exploring the association between different body weights, varying metabolic statuses, and the occurrence of CVD in the Chinese population.
Are different metabolic overweight/obesity phenotypes associated with an increased prevalence of cardiovascular disease in a Chinese population?
Cross-Sectional (n=9,075)
Yes
Are different metabolic overweight/obesity phenotypes associated with an increased prevalence of cardiovascular disease in a Chinese population?
Odds Ratio: 2.44 (95% CI 1.73–3.43)
p-value: p=<0.0001
Both obesity and metabolic abnormalities, particularly hypertension and increased waist circumference in the elderly, are independently associated with a higher prevalence of cardiovascular disease in the Chinese population.
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Highlights need for metabolic phenotyping in obesity-related CVD risk assessment; extends data to Chinese adults but leaves causality open.
Qiu et al. (2024) conducted a cross-sectional in Cardiovascular disease (n=9,075). Metabolically unhealthy overweight/obesity (MUO) vs. Metabolically healthy non-overweight/obesity (MHNO) was evaluated on Prevalence of cardiovascular disease (OR 2.44, 95% CI 1.73-3.43, p=<0.0001). Metabolically unhealthy overweight/obesity was significantly associated with a higher prevalence of cardiovascular disease compared to metabolically healthy non-overweight/obesity (OR 2.44).
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