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April 23, 2026BMC Cardiovascular DisordersOpen Access

Associations between metabolic obesity phenotypes and incident cardiovascular disease in middle-aged and elderly Chinese individuals

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Authors

KWKangwei WangTZTing ZhangYLYa Lin

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Overview

Investigates metabolic obesity phenotypes' effects on cardiovascular disease risk in middle-aged and elderly Chinese individuals, highlighting health implications.

Key Points

  • This research aims to examine how different obesity phenotypes affect the risk of cardiovascular disease in a specific demographic.
  • Utilized longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS).
  • Applied weighted logistic regression, Poisson regression, and restricted cubic spline models to evaluate associations.
  • Classified individuals based on body mass index (BMI) and waist circumference (WC) to assess CVD risk.
  • Incident cardiovascular disease differed significantly across metabolic obesity phenotypes (p<0.001).
  • All non-reference metabolic obesity phenotypes showed increased CVD risk, particularly metabolically unhealthy obesity (relative risk: 2.64).
  • Increasing waist circumference was consistently linked to higher CVD risk across all metabolic groups.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69e9b71b85696592c86eb2a8https://doi.org/10.1186/s12872-026-05849-y
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