Key result
Moyamoya disease during pregnancy is linked to a 50% rate of intracranial hemorrhage.
Why the study?
Pregnancy in patients with moyamoya disease is complicated by a high risk of intracranial haemorrhage, but neurological outcomes related to delivery methods are unclear.
What are the neurological outcomes and optimal delivery methods for pregnant patients with moyamoya disease?
What are the neurological outcomes and optimal delivery methods for pregnant patients with moyamoya disease?
Pregnancy in moyamoya disease carries a high risk of intracranial haemorrhage, though delivery method does not appear to alter maternal outcome.
May signal high ICH risk in moyamoya pregnancies; leaves optimal delivery methods unresolved.
SummaryMoyamoya disease is diagnosed on the angiographic findings of intracranial carotid artery stenosis or occlusion and a fine network of collateral vessels at the base of the brain. It commonly presents as a subarachnoid haemorrhage in a teenager or young adult. Of ten reports of pregnancy complicated by moyamoya disease, five patients suffered intracranial haemorrhage during pregnancy. In only two patients were there no changes in their neurological status. None of the neurological complications were associated with hypertension. The outcome for the patient appears to be the same if delivery is by caesarean section or by assisted vaoinal delivery.
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Fayle et al. (1992) conducted a review in Moyamoya disease in pregnancy (n=10). Pregnancy was evaluated on Intracranial haemorrhage. Among 10 reported cases of pregnancy complicated by moyamoya disease, 50% of patients suffered intracranial hemorrhage during pregnancy.
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