Key result
Hemodialysis in stage 5 CKD is linked to higher AAC, CIMT, and cardiac valvular calcifications.
Why the study?
Patients with stage 5 CKD have an increased atherosclerotic burden, but established radiological methods for investigating aortic calcification are costly and primarily used for research.
Is the prevalence of cardiovascular imaging risk markers (AAC, CIMT, CVCs) higher in patients with stage 5D CKD receiving hemodialysis compared to stage 5 CKD not on dialysis?
Observational (n=60)
Is the prevalence of cardiovascular imaging risk markers (AAC, CIMT, CVCs) higher in patients with stage 5D CKD receiving hemodialysis compared to stage 5 CKD not on dialysis?
Patients with stage 5D CKD on hemodialysis have a higher prevalence of cardiovascular calcification and atherosclerotic markers compared to those with stage 5 CKD not on dialysis.
May support vascular imaging surveillance in stage 5D CKD; leaves open causality and need for prospective trials.
Background: Patients with stage 5 chronic kidney disease (CKD) have an increased atherosclerotic burden. Several radiological methods have been used to investigate aortic calcification. Such methods are costly and are primarily used for clinical research purposes. Noninvasive imaging techniques may be used to monitor the progression and/or regression of coronary atherosclerosis and thus possibly to evaluate its effectiveness. Aim and Objectives: Cardiovascular (CV) risk assessment with the help of imaging modalities (abdominal aortic calcification (AAC) scoring, carotid intima-media thickness (CIMT), cardiac valvular calcifications (CVCs)) in patients with stage 5 CKD and comparison with patients with stage 5 CKD receiving hemodialysis. Materials and Methods: This study included 30 patients with stage 5 CKD not on dialysis (Group 1) and 30 patients with stage 5D CKD receiving hemodialysis. Results: The prevalence of AAC scoring, CIMT, and CVCs in the present study was more in the stage 5D CKD receiving hemodialysis group as compared to the stage V CKD group. Conclusion: The present study findings conclude lateral abdominal x-ray to measure aortic calcification can be used to assess vascular calcification (intimal and medial) in patients with CKD.
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Agarwal et al. (2023) conducted an observational in Stage 5 chronic kidney disease (n=60). Hemodialysis vs. Not on dialysis was evaluated on Prevalence of abdominal aortic calcification, carotid intima-media thickness, and cardiac valvular calcifications. Hemodialysis in stage 5 chronic kidney disease was associated with a higher prevalence of abdominal aortic calcification, carotid intima-media thickness, and cardiac valvular calcifications.
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