Key result
Surgical excision of recurrent cutaneous breast angiosarcoma yields 25-month disease-free survival in a single case.
Why the study?
Breast angiosarcomas frequently arise after radiation therapy and typically recur within the first postsurgical year, but late recurrence patterns are not well documented.
Case Report (n=1)
No
This case highlights the possibility of late recurrence of breast angiosarcoma and the need for careful long-term follow-up of skin alterations after breast conservative treatment with radiotherapy.
May warrant extended skin surveillance after breast radiotherapy; leaves open optimal management of late recurrent angiosarcoma.
Breast angiosarcomas are malignant tumours of the vascular endothelium that arise frequently following radiation therapy. Their clinical and radiological aspects are highly heterogeneous. The current study reports an unusual case, never previously reported, of a late recurrent breast angiosarcoma occurring in an 83-year old female patient 11 years after a breast-conserving surgery followed by radiation therapy for an invasive ductal carcinoma, and 5 years after her initial angiosarcoma excision. The first physician to examine the patient noted a palpable mass near the scar and, following ultrasonography, described the breast lesion as suggestive of an abscess, despite the previous history of neoplasia. Typically, recurrences of breast angiosarcoma occur within the first postsurgical year. The present patient remains alive at 25 months after her last surgical treatment, and no evidence of any local or distant disease is observable.
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Famà et al. (2016) conducted a case report in Late recurrent cutaneous breast angiosarcoma (n=1). Surgical excision was evaluated on Disease-free survival / clinical local recurrence or distant metastases. Surgical excision of a late recurrent cutaneous breast angiosarcoma in an 83-year-old woman resulted in a 25-month disease-free survival with no evidence of local or distant recurrence.
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