Key result
High-risk pregnancy history linked to ~14-fold more non-dipping blood pressure patterns and increased arterial stiffness.
Why the study?
Do women with a history of high-risk pregnancies develop arterial stiffness and non-dipping blood pressure patterns?
Cohort (n=100)
Yes
Do women with a history of high-risk pregnancies develop arterial stiffness and non-dipping blood pressure patterns?
Absolute Event Rate: 56% vs 4%
The study aims to determine if high-risk pregnancies lead to arterial stiffness and abnormal blood pressure dipping to guide long-term preventive cardiovascular measures.
May identify arterial stiffness and nondipping in high-risk postpartum women; leaves open whether these predict future CVD events.
Pregnant women who had passed through high risk pregnancies, manifested as Preeclampsia, giving birth to low weight babies, gestational diabetes mellitus and peripartum cardiomyopathy, are expected to be at high risk of developing subsequent future cardiovascular diseases and events.We need to know if the high risk pregnant women will establish an Arterial Stiffness status and lose their normal nocturnal dipping of blood pressure in the period following these pregnancies.This will confirm the damage created by the heavy burden -of the high risk pregnancies -manifestations and will allow cardiologists and primary health clinicians to put these women for life preventive measures.This type of study was done using the new ABPM monitoring technology to detect blood pressure, dipping-non dipping changes and Arterial stiffness.
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A 2017 study conducted a cohort in High risk pregnancy (n=100). High risk pregnancy vs. Normal pregnancy was evaluated on Development of non-dipping nocturnal blood pressure pattern. Women with a history of high-risk pregnancies developed more non-dipping blood pressure patterns (56% vs 4%) and arterial stiffness (8% vs 0%) over 5 years compared to women with normal pregnancies.
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