Key result
Post-AMI 30-day mortality falls ~9% per year from 1995 to 1999.
Why the study?
Changes in 30 day and one year mortality after acute myocardial infarction and lipid level management before the National Service Framework for coronary heart disease were not quantified in this English health district.
Observational (n=4,912)
No
Effect estimate: 9% reduction per year (95% CI 4% to 13%)
p-value: p=0.012
Between 1995 and 1999, there was a significant temporal decline in 30-day and 1-year mortality after acute myocardial infarction, accompanied by improved lipid management and target achievement.
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Mortality after AMI declined 9%/year with rising lipid control pre-NSF; leaves open whether secular trends or unmeasured factors drove gains.
James S. Harrop (2002) conducted an observational in Acute myocardial infarction (n=4,912). Year of admission (1995-1999) vs. Earlier years of admission was evaluated on 30 day mortality (9% reduction per year, 95% CI 4% to 13%, p=0.012). The five-year period from 1995 to 1999 saw a progressive reduction in 30-day mortality after acute myocardial infarction of 9% per year (95% CI, 4% to 13%; P=0.012).
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