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June 1, 1996Circulation

Male sex was associated with similar overall 28-day fatality rates compared to female sex (49.8% vs 48.5%), but a significantly higher proportion of out-of-hospital deaths (74.3% vs 67.8%, P=0.0004).

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Population

5,542 episodes of nonfatal definite myocardial infarction and coronary deaths in 25- to 64-year-old…

Design

Cohort

Follow-up

28-day

Key result

Male sex was associated with similar overall 28-day fatality rates compared to female sex (49.8% vs 48.5%), but a significantly higher proportion of out-of-hospital deaths (74.3% vs 67.8%, P=0.0004).

Authors

HTHugh Tunstall‐PedoeCMCaroline MorrisonMWMark Woodward

Discussion

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Overview

Association of male sex with higher out-of-hospital deaths supports targeted prevention research; leaves open causal mechanisms and intervention trials.

Study Design

Type

Observational (n=5,542)

Multicenter

No

Structured PICO

P
Population
5,542 episodes of nonfatal definite myocardial infarction and coronary deaths in 25- to 64-year-old residents of north Glasgow (3,991 in men, mean age 55.5; 1,551 in women, mean age 57.0).
O
Outcome
28-day fatality rates, out-of-hospital deaths, and hospital fatality rateshard clinical

Main Result

Absolute Event Rate: 49.8% vs 48.5%

While overall 28-day fatality from acute coronary events is similar between sexes, men are more likely to die out of hospital, whereas women experience higher mortality after hospital admission.

Cite This Study

Tunstall‐Pedoe et al. (1996) conducted an observational in Myocardial infarction and coronary deaths (n=5,542). Male sex vs. Female sex was evaluated on Overall 28-day fatality rate. Male sex was associated with similar overall 28-day fatality rates compared to female sex (49.8% vs 48.5%), but a significantly higher proportion of out-of-hospital deaths (74.3% vs 67.8%, P=0.0004).

synapsesocial.com/papers/6a0b3d7be1320844825d2bf7https://doi.org/10.1161/01.cir.93.11.1981
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