Key result
Time on active surveillance for prostate cancer is linked to ~13% lower cancer-specific anxiety.
Why the study?
Cancer specific anxiety during active surveillance of low risk prostate cancer remains understudied.
Does cancer-specific anxiety change over time in men undergoing active surveillance for prostate cancer?
Population
413 men enrolled in active surveillance for prostate cancer at a single tertiary care center
Comparison
Not applicable; observational assessment of anxiety over time
Design
Prospective cohort study using quality of life surveys
Follow-up
Median 3.7 years
Authors
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Anxiety may decline over time on active surveillance; hypothesis-generating and should not yet change practice.
Cohort (n=413)
No
Does cancer-specific anxiety change over time in men undergoing active surveillance for prostate cancer?
Odds Ratio: 0.87 (95% CI 0.79–0.95)
p-value: p=0.003
In men undergoing active surveillance for prostate cancer, cancer-specific anxiety is initially moderate but significantly decreases over time.
Marzouk et al. (2018) conducted a cohort in Prostate cancer (n=413). Active surveillance was evaluated on Cancer specific anxiety (OR 0.87, 95% CI 0.79-0.95, p=0.003). Time on active surveillance for prostate cancer was associated with a significant decrease in cancer-specific anxiety (OR 0.87; 95% CI 0.79-0.95; p=0.003).
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