Key result
Review compares unilateral versus bilateral antegrade brain perfusion to reduce neurological complications in aortic surgery.
Why the study?
There are no clear guidelines regarding the management and brain protection methods for patients operated on the aortic arch.
Does antegrade unilateral brain perfusion compared to bilateral perfusion reduce neurological complications in patients undergoing aortic arch surgery?
Does antegrade unilateral brain perfusion compared to bilateral perfusion reduce neurological complications in patients undergoing aortic arch surgery?
This review summarizes current evidence on unilateral versus bilateral antegrade cerebral perfusion for brain protection during aortic arch surgery, an area currently lacking clear guidelines.
No clear guidelines on unilateral versus bilateral antegrade cerebral perfusion advise caution in aortic arch surgery; leaves open need for comparative trials.
Aortic arch surgery is one of the most challenging field of cardiovascular surgery. Reconstructive interventions on the aortic arch are associated with high risks due to the peculiarities of anatomy and technical complexity of surgical intervention. Antegrade cerebral perfusion in combination with hypothermia is widely used to protect the brain during aortic arch surgery. Antegrade cerebral perfusion can be performed in unilateral or bilateral way. Now, there is no clear guidelines regarding the management of patients operated on the aortic arch. This review highlights the main methods of protecting the brain during aortic arch surgery and shows the results of the studies comparing antegrade unilateral brain perfusion with bilateral one. We reviewed rationale of various researchers in choosing two proposed methods to reduce the risk of neurological complications.
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Khomushku et al. (2025) conducted a review in Aortic arch surgery. Antegrade unilateral brain perfusion vs. Bilateral brain perfusion was evaluated on Neurological complications. This review highlights methods of brain protection during aortic arch surgery, comparing antegrade unilateral with bilateral brain perfusion to reduce the risk of neurological complications.
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