Observational study reveals frequent asymptomatic optic radiation lesions in acute isolated optic neuritis, highlighting widespread occult posterior visual pathway damage.
Magnetic resonance imaging revealed asymptomatic lesions in white matter regions corresponding with the optic radiations in 20 of 28 patients (71%) with clinically isolated optic neuritis. In contrast to the findings with symptomatic lesions, there was no relationship between the latency of the visual evoked potential and the presence of these asymptomatic posterior visual pathway lesions.
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Hornabrook et al. (1992) studied this question.
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