Key result
TAVI followed by lung resection 3 weeks later succeeds without complications in severe AS.
Why the study?
The safety and efficacy of pulmonary resection for lung cancer following transcatheter aortic valve implantation (TAVI) for severe aortic valve stenosis were not established.
Case Report (n=1)
No
Two-stage therapy with TAVI followed by pulmonary resection is a feasible and safe approach for patients with severe aortic stenosis and concurrent lung cancer.
Supports staged TAVI before lung resection in select high-risk patients; hypothesis-generating and should not yet change practice.
An 82-year-old woman was referred to our hospital because of dyspnea on effort. Echocardiography revealed severe aortic valve stenosis (AS). Simultaneously, chest computed tomography (CT) revealed a 19-mm nodule in the lower lobe of the right lung, and bronchoscopic biopsy revealed adenocarcinoma. She underwent transcatheter aortic valve implantation (TAVI) for severe AS. Three weeks later, she underwent lower lobectomy of the right lung and mediastinal dissection for the lung cancer. Her postoperative course was good, and she was discharged 8 days postoperatively. In conclusion, we encountered a patient who successfully underwent pulmonary resection for lung cancer following TAVI for severe AS. We suggest that pulmonary resection following TAVI is an acceptable choice for lung cancer in patients with severe AS because of the lack of a need for cardiopulmonary bypass, the high safety and efficacy of two-stage therapy, and the short period between the two therapies.
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Komatsu et al. (2018) conducted a case report in Severe aortic valve stenosis and lung cancer (n=1). Transcatheter aortic valve implantation (TAVI) followed by pulmonary resection was evaluated on Clinical outcome of two-stage therapy. An 82-year-old woman with severe aortic valve stenosis and lung cancer successfully underwent pulmonary resection 3 weeks after transcatheter aortic valve implantation without complications.
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