Key result
ACS mortality in Serbia significantly declines for both genders between 2006 and 2016.
Why the study?
The study was conducted to analyse and compare the trends of mortality rates from ACS in the Republic of Serbia and the territory of the Jablanica District from 2006 to 2020.
Observational
Acute coronary syndrome mortality rates have shown a decreasing trend in Serbia between 2006 and 2016, with notable reductions among females in the Jablanica District.
ACS mortality decline in Serbia is encouraging; observational data leaves open causal drivers and generalizability.
Clinical conditions that are characterized by a sudden and critical reduction in blood flow with consequent ischemia and/or necrosis of the myocardium, and are caused by rupture or erosion of atherosclerotic plaque, are considered acute coronary syndrome (ACS). The aim of the paper is to analyse the trend of mortality rates from ACS in the Republic of Serbia and in the territory of the Jablanica District from 2006 to 2020 and to compare the trends. The research is a descriptive-epidemiological study. Mortality rates are shown in the form of crude rates (Crude rate - CR), as well as age-standardized rates in the territory of Europe and the world (Age standardized rate - ASR-E and ASR-W). In order to monitor the trend of dying from ACS in the Republic of Serbia and the Jablanica District in men and women, CR and standardized ASR-E rates were used using the statistical program Joinpoint trend analysis software. A value of p<0.05 was considered statistically significant. After analyzing the mortality rates on the territory of the Republic of Serbia in a fifteen-year period, the highest values of the female mortality rate were determined in 2006 (CR 83.8, ASR-E 51.4 and ASR-W 32.93), while the lowest values were present in 2016 (CR 50.1, ASR-E 25.5 and ASR-W 15.7). In the territory of the Jablanica District, the highest values for females were in 2009 (CR 110.1, ASR-E 61.5 and ASR-W 38.6), while the lowers were in 2019 (CR 42.3, ASR-E 19.6 and ASR-W 11.6). After the analysis of mortality rates in the territory of the Republic of Serbia, the highest values of the mortality rates for males were determined in 2006 (CR 132, ASR-E 106.9 i ASR-W 72.1), while the lowest values were registered in 2020 (CR 76.3, ASR-E 52.5 and ASR-W 34.9). In the territory of the Jablanica District, for males, the highest values refer to the year 2008 (CR 134.3, ASR-E 99.6 and ASR-W 65.2), and the lowest to 2014 (CR 51. ASR-E 34.5 and ASR-W 24.4). There is an evident trend of decreasing ACS mortality rates for both genders in the territory of the Republic of Serbia in the period 2006-2016 and for the female gender in the territory of the Jablanica District during the entire observed cycle.
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Ivan Vučić (2024) conducted an observational in Acute coronary syndrome. Time (2006-2020) was evaluated on Trend of mortality rates from acute coronary syndrome (Crude rate and Age-standardized rate) (p=<0.05). Mortality rates from acute coronary syndrome significantly decreased for both genders in the Republic of Serbia between 2006 and 2016, and for females in the Jablanica District from 2006 to 2020.
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