Key result
Open radical nephrectomy with IVC thrombectomy achieves five-month disease-free status in primary renal leiomyosarcoma.
Why the study?
Primary renal leiomyosarcoma are rare, aggressive tumors with especially uncommon vascular involvement by tumor thrombus.
Case Report (n=1)
Complete surgical resection of primary renal leiomyosarcoma with IVC tumor thrombus can result in successful short-term disease-free survival.
Surgical resection feasible in rare PRLMS with IVC thrombus; leaves open optimal adjuvant therapy and survival data.
Primary renal leiomyosarcoma (PRLMS) are rare, aggressive smooth muscle tumors, and vascular involvement with tumor thrombus is especially uncommon. We present a case of a 66-year-old male with hematuria and abdominal pain found to have a 10.5 cm left renal mass with thrombus extending into the renal vein and inferior vena cava (IVC). The patient underwent open radical nephrectomy with IVC thrombectomy. Histopathology confirmed grade 2 leiomyosarcoma with negative surgical margins, The patient recovered uneventfully and remains disease-free five months postoperatively, highlighting the important of complete resection.
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Druck et al. (2025) conducted a case report in Primary renal leiomyosarcoma with renal vein and inferior vena cava tumor thrombus (n=1). Open radical nephrectomy with IVC thrombectomy was evaluated on Disease-free status. Open radical nephrectomy with IVC thrombectomy resulted in an uneventful recovery and disease-free status at five months postoperatively in a patient with primary renal leiomyosarcoma.
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