Key result
Prone MDCT detects LAA thrombi with 100% sensitivity and specificity versus TEE.
Why the study?
The study was conducted to evaluate the diagnostic performance of prone position cardiac MDCT in detecting LAA thrombi and differentiating thrombus from circulatory stasis compared with criterion-standard TEE.
Does prone position cardiac MDCT accurately detect LAA thrombus and differentiate it from circulatory stasis compared to TEE in patients with suspected LAA stasis/thrombus?
Observational (n=53)
Does prone position cardiac MDCT accurately detect LAA thrombus and differentiate it from circulatory stasis compared to TEE in patients with suspected LAA stasis/thrombus?
Prone-position MDCT is highly accurate for differentiating circulatory stasis from LAA thrombus and may serve as a non-invasive alternative to TEE.
Prone MDCT showed perfect accuracy versus TEE for LAA thrombus versus stasis; leaves open whether it can replace TEE in broader practice.
OBJECTIVE: The purpose of this study was to assess the diagnostic performance of prone position cardiac multidetector computed tomography (MDCT) in the detection of left atrial appendage (LAA) thrombi and to make differentiate between thrombus and circulatory stasis using transesophageal echocardiography (TEE) as the criterion-standard imaging modality. METHODS: From December 2014 to April 2016, 53 consecutive patients were admitted to the hospital because of circulatory stasis or/and thrombus. All patients underwent prone-position MDCT and TEE. Prone-position MDCT and TEE sensitivity, specificity, positive predictive value, and negative predictive value were calculated. RESULTS: For the MDCT scan in the prone position, the sensitivity, specificity, positive predictive value, and negative predictive value results were 100%, 100%, 100%, and 100%, respectively. CONCLUSIONS: Multidetector computed tomography scanning in the prone position differentiates circulatory stasis and LAA thrombus, is clinically useful for detecting and ruling out LAA thrombus, and may be an alternative to TEE as a diagnostic tool.
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Kantarcı et al. (2019) conducted an observational in Circulatory stasis or/and thrombus in left atrial appendage (n=53). Prone position cardiac multidetector computed tomography (MDCT) vs. Transesophageal echocardiography (TEE) was evaluated on Detection of left atrial appendage (LAA) thrombi and differentiation between thrombus and circulatory stasis. Prone-position cardiac multidetector computed tomography demonstrated 100% sensitivity and specificity for detecting left atrial appendage thrombi compared to transesophageal echocardiography.
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