Key result
Dual-enhanced cardiac CT demonstrated 96% sensitivity and 100% specificity for detecting left atrial appendage thrombi and circulatory stasis compared to transesophageal echocardiography.
Why the study?
Does dual-enhanced cardiac CT accurately detect left atrial appendage thrombus compared to transesophageal echocardiography in patients with stroke?
Observational (n=83)
Does dual-enhanced cardiac CT accurately detect left atrial appendage thrombus compared to transesophageal echocardiography in patients with stroke?
Effect estimate: Sensitivity 96%, Specificity 100% (95% CI 78% to 99% for sensitivity, 92% to 100% for specificity)
Dual-enhanced cardiac CT provides high sensitivity and specificity for detecting left atrial appendage thrombus in stroke patients, offering a noninvasive alternative to transesophageal echocardiography.
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Supports noninvasive LAA thrombus detection in stroke; leaves open prospective validation before replacing TEE.
Hur et al. (2011) conducted an observational in Stroke (n=83). Dual-enhanced cardiac CT vs. Transesophageal echocardiography was evaluated on Detection of thrombi and circulatory stasis in the left atrial appendage (Sensitivity 96%, Specificity 100%, 95% CI 78% to 99% for sensitivity, 92% to 100% for specificity). Dual-enhanced cardiac CT demonstrated 96% sensitivity and 100% specificity for detecting left atrial appendage thrombi and circulatory stasis compared to transesophageal echocardiography.
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