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September 24, 2019VASA

Carotid endarterectomy and carotid artery stenting yielded similar 8-year stroke-free survival rates (98% vs 100%, P=0.271) for the treatment of recurrent carotid artery stenosis.

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Why the study?

The study was conducted to evaluate perioperative and long-term outcomes in patients undergoing carotid endarterectomy or stenting for symptomatic or asymptomatic high-grade restenosis of the internal carotid artery.

Does carotid endarterectomy or stenting provide better perioperative and long-term outcomes in patients with recurrent carotid artery stenosis?

Population

111 patients with recurrent internal carotid artery stenosis

Comparison

Carotid endarterectomy (CEA) vs carotid artery stenting (CAS)

Design

Retrospective single-centre case series

Follow-up

8 years

Key result

Carotid endarterectomy and carotid artery stenting yielded similar 8-year stroke-free survival rates (98% vs 100%, P=0.271) for the treatment of recurrent carotid artery stenosis.

Authors

WAWael AhmadHDHiba DeebCOChristoph Otto

Discussion

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Member takes

Overview

Both CEA and CAS for carotid restenosis show low periprocedural risk and high stroke-free survival; leaves open optimal strategy in prospective studies.

Study Design

Type

Observational (n=111)

Multicenter

No

Structured PICO

Does carotid endarterectomy or stenting provide better perioperative and long-term outcomes in patients with recurrent carotid artery stenosis?

P
Population
111 patients with recurrent internal carotid artery stenosis treated with carotid endarterectomy or stenting, evaluated for perioperative and long-term outcomes up to 8 years.
E
Exposure
Carotid endarterectomy (CEA) or carotid artery stenting (CAS)
C
Comparator
CEA compared to CAS
O
Outcome
Perioperative stroke or death, and long-term stroke-free survivalhard clinical

Main Result

Absolute Event Rate: 98% vs 100%

p-value: p=0.271

Redo-CEA and CAS for recurrent carotid artery stenosis demonstrate favorable periprocedural and long-term outcomes with no significant difference in stroke-free survival between the two approaches.

Cite This Study

Ahmad et al. (2019) conducted an observational in Recurrent carotid artery stenosis (n=111). Carotid endarterectomy (CEA) vs. Carotid artery stenting (CAS) was evaluated on Stroke-free survival at 8 years (p=0.271). Carotid endarterectomy and carotid artery stenting yielded similar 8-year stroke-free survival rates (98% vs 100%, P=0.271) for the treatment of recurrent carotid artery stenosis.

synapsesocial.com/papers/6aaa12ccf6e8aa835a481eb8https://doi.org/10.1024/0301-1526/a000824
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis1991 · 8,507 citations
  2. 2Understanding and managing in-stent restenosis: a review of clinical data, from pathogenesis to treatment2016 · 397 citations
  3. 3Stenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis2010 · 3,007 citations
  4. 4Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial2012 · 404 citations