Key result
Conventional aortic valve replacement shows ~83% 5-year survival overall but lower survival in octogenarians.
Why the study?
The increasing elderly population and new treatment options for aortic valve disease necessitate knowledge of contemporary outcomes after conventional aortic valve surgery to guide treatment allocation.
What is the short- and long-term survival after conventional aortic valve replacement in octogenarians and high-risk subgroups?
Population
1525 patients undergoing aortic valve replacement from 1999 to 2010 including 361 octogenarians and high-risk subgroups
Comparison
Conventional aortic valve surgery outcomes in elderly and high-risk patients
Design
Cohort study from a single-center database
Authors
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May support continued surgical AVR in octogenarians; leaves open EuroSCORE accuracy for TAVI allocation.
Cohort (n=1,525)
No
What is the short- and long-term survival after conventional aortic valve replacement in octogenarians and high-risk subgroups?
Conventional aortic valve surgery demonstrates excellent short- and long-term survival in octogenarians and high-risk patients, suggesting the logistic EuroSCORE may overestimate operative risk when allocating patients to TAVI.
Mølstad et al. (2012) conducted a cohort in aortic valvular disease (n=1,525). Conventional aortic valve replacement was evaluated on all-cause mortality (short-term mortality and 5-year survival). Conventional aortic valve replacement resulted in 2.2% short-term mortality and 83.1% 5-year survival overall, with 3.9% short-term mortality and 68.1% 5-year survival in octogenarians.
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